Selected Publications
Vickers A, Tewary M, Laddach A, Poletti M, Salameti V, Fraternali F, Danovi D, Watt FM. 'Plating human iPSC lines on micropatterned substrates reveals role for ITGB1 nsSNV in endoderm formation.' Stem Cell Reports. 2021 Nov 9;16(11):2628-2641. doi: 10.1016/j.stemcr.2021.09.017. Epub 2021 Oct 21. PMID: 34678211
Geraldine M. Jowett, Michael D. A. Norman, Tracy T. L. Yu, Patricia Rosell Arévalo, Dominique Hoogland, Suzette Lust, Emily Read, Eva Hamrud, Nick J. Walters, Umar Niazi, Matthew Wai Heng Chung, Daniele Marciano, Omer Serhan Omer, Tomasz Zabinski, Davide Danovi, Graham M. Lord, Jöns Hilborn, Nicholas D. Evans, Cécile A. Dreiss, Laurent Bozec, Oommen P. Oommen, Christian D. Lorenz, Ricardo M.P. da Silva, Joana F. Neves, Eileen Gentleman 'ILC1-derived TGFβ1 drives intestinal remodelling' Nat Mater. 2020 Sep 7. doi: 10.1038/s41563-020-0783-8
Haneen Alsehli, Fuad Mosis, Christopher Thomson, Eva Hamrud, Erika Wiseman, Eileen Gentleman, Davide Danovi 'An integrated pipeline for high-throughput screening and profiling of spheroids using simple live image analysis of frame to frame variations' Methods 2020-05 | DOI: 10.1016/j.ymeth.2020.05.017
Wiseman E, Zamuner A, Tang Z, Rogers J, Munir S, Di Silvio L, Danovi D, Veschini L. 'Integrated Multiparametric High-Content Profiling of Endothelial Cells.' SLAS Discov. 2019 Mar;24(3):264-273. doi: 10.1177/2472555218820848. Epub 2019 Jan 25.
Vigilante, A., Laddach, A., Moens, N., Meleckyte, R., Leha, A., Ghahramani, A., Culley, O. J., Kathuria, A., Hurling, C., Vickers, A., Wiseman, E., Tewary, M., Zandstra, P. W., Durbin, R., Fraternali, F., Stegle, O., Birney, E., Luscombe, N. M., HipSci Consortium, Danovi, D. & Watt F. Identifying Extrinsic versus Intrinsic Drivers of Variation in Cell Behavior in Human iPSC Lines from Healthy Donors 19 Feb 2019, In : Cell Reports. 26, 8, p. 2078-2087.e3
Ong J, Serra MP, Segal J, Cujba AM, Ng SS, Butler R, Millar V, Hatch S, Zimri S, Koike H, Chan K, Bonham A, Walk M, Voss T, Heaton N, Mitry R, Dhawan A, Ebner D, Danovi D, Nakauchi H, Rashid ST. 'Imaging-Based Screen Identifies Laminin 411 as a Physiologically Relevant Niche Factor with Importance for i-Hep Applications.' Stem Cell Reports. 2018 Mar 13;10(3):693-702. doi: 10.1016/j.stemcr.2018.01.025. Epub 2018 Mar 1.
Ghahramani A, Donati G, Luscombe NM, Watt FM. 'Epidermal Wnt signalling regulates transcriptome heterogeneity and proliferative fate in neighbouring cells.' Genome Biol. 2018 Jan 15;19(1):3. doi: 10.1186/s13059-017-1384-y. PMID: 29334988
Kilpinen H, Goncalves A, Leha A, Afzal V, Alasoo K, Ashford S, Bala S, Bensaddek D, Casale FP, Culley OJ, Danecek P, Faulconbridge A, Harrison PW, Kathuria A, McCarthy D, McCarthy SA, Meleckyte R, Memari Y, Moens N, Soares F, Mann A, Streeter I, Agu CA, Alderton A, Nelson R, Harper S, Patel M, White A, Patel SR, Clarke L, Halai R, Kirton CM, Kolb-Kokocinski A, Beales P, Birney E, Danovi D, Lamond AI, Ouwehand WH, Vallier L, Watt FM, Durbin R, Stegle O, Gaffney DJ. 'Corrigendum: Common genetic variation drives molecular heterogeneity in human iPSCs.' Nature. 2017 Jun 29;546(7660):686. doi: 10.1038/nature23012. PMID: 28614302
Walko G, Woodhouse S, Pisco AO, Rognoni E, Liakath-Ali K, Lichtenberger BM, Mishra A, Telerman SB, Viswanathan P, Logtenberg M, Renz LM, Donati G, Quist SR, Watt FM. 'A genome-wide screen identifies YAP/WBP2 interplay conferring growth advantage on human epidermal stem cells.' Nat Commun. 2017 Mar 23;8:14744. doi: 10.1038/ncomms14744. PMID: 28332498
Hayes TF, Benaich N, Goldie SJ, Sipilä K, Ames-Draycott A, Cai W, Yin G, Watt FM. 'Integrative genomic and functional analysis of human oral squamous cell carcinoma cell lines reveals synergistic effects of FAT1 and CASP8 inactivation.' Cancer Lett. 2016 Dec 1;383(1):106-114. doi: 10.1016/j.canlet.2016.09.014. PMID: 27693639
Kerz M, Folarin A, Meleckyte R, Watt FM, Dobson RJ, Danovi D. 'A Novel Automated High-Content Analysis Workflow Capturing Cell Population Dynamics from Induced Pluripotent Stem Cell Live Imaging Data.' J Biomol Screen. 2016 Jun 2. pii: 1087057116652064. PMID: 27256155
Reimer A, Vasilevich A, Hulshof F, Viswanathan P, van Blitterswijk CA, de Boer J, Watt FM. 'Scalable topographies to support proliferation and Oct4 expression by human induced pluripotent stem cells.' Sci Rep. 2016 Jan 13;6:18948. doi: 10.1038/srep18948. PMID: 26757610
Viswanathan P, Guvendiren M, Chua W, Telerman SB, Liakath-Ali K, Burdick JA, Watt FM. 'Mimicking the topography of the epidermal-dermal interface with elastomer substrates.' Integr Biol (Camb). 2015 Dec 11. Viswanathan P, Guvendiren M, Chua W, Telerman SB, Liakath-Ali K, Burdick JA, Watt FM. PMID: 26658424
Leha A, Moens N, Meleckyte R, Culley OJ, Gervasio MK, Kerz M, Reimer A, Cain SA, Streeter I, Folarin A, Stegle O, Kielty CM; HipSci Consortium, Durbin R, Watt FM, Danovi D. 'A high-content platform to characterise human induced pluripotent stem cell lines.' Methods. 2015 Nov 25. pii: S1046-2023(15)30153-5. doi: 10.1016/j.ymeth.2015.11.012. PMID: 26608109