iPSC-derived endothelial cells
iPSC-ECFC (Endothelial cell-forming colonies derived from induced pluripotent stem cells) treated with VEGF.
Imaged with Operetta CLS 40x Water Immersion Objective. Nuclei (Hoechst), cell junctions (594) and spots (488).
Image courtesy Lorenzo Veschini
iPSC cultured on micro patterns
Recapitulating embryonic development in vitro using human-induced pluripotent stem cells. Cells confined in space are exposed to morphogens mirroring early development.
Imaged with Operetta CLS 40x Water Immersion Objective. Differentiation markers stained in different colours.
Image courtesy Alice Vickers, PhD
Human cancer tumoroids
Use of human iPSC-derived macrophages that reflect tissue-resident macrophages to assess their impact on the cancer stem cell phenotype of breast cancer cells in organoid cultures.
Imaged with Operetta CLS 40x Water Immersion Objective. Nuclei (DAPI), basal cancer marker (555), luminal cancer marker (647), E-cadherin (488).
Image courtesy Aitor Arteagabeitia, PhD student
Image courtesy of Inês Martins Tomás, PhD Student